blockers
• Concomitant use of Progesic and warfarin may result in increased risk of bleeding complications.
• Esomeprazole inhibits gastric acid secretion and may interfere with the absorption of drugs where gastric pH is an important determinant of bioavailability (eg, ketoconazole, iron salts and digoxin).
Over Dose
There is no clinical data on overdosage with Progesic.
Overdose of Naproxen: Significant naproxen overdosage may be characterized by lethargy, drowsiness, epigastric pain, abdominal discomfort, heartburn, indigestion, nausea, transient alterations in liver function, hypoprothrombinemia, renal dysfunction, metabolic acidosis, apnea, vomiting etc.
Overdose of Esomeprazole: The major signs of acute toxicity were reduced motor activity, changes in respiratory frequency, tremor and intermittent clonic convulsions etc
Commercial Pack
Progesic 375 Tablet: Each box contains 3 Alu-Alu blister strips of 10 tablets.
Progesic 500 Tablet: Each box contains 7 Alu-Alu blister strips of 4 tablets.
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